AbbVie announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio. Syndesi Therapeutics has raised a total of 26.2M in funding over 3 rounds. Use Slintel to connect with top decision-makers at Syndesi Therapeutics. The company's drugs can modulate the synaptic vesicl, eu fugiat nulla pariatur. Developer of drug molecules designed to treat cognitive impairment. 17,000,000 Venture capital (Series A) FierceBiotech. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Place de lUniversit 16 bte 27 "There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases," saidTom Hudson, M.D., senior vice president, R&D, chief scientific officer, AbbVie. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Syndesi Therapeutics is building upon a rich legacy of research on SV2A conducted at UCB. To connect with Syndesi Therapeutics employee register on SignalHire. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2021 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its subsequent Quarterly Reports on Form 10-Q. Funding Rounds Number of Funding Rounds 3 Total Funding Amount 26.2M Syndesi's unique molecules act pre-synaptically to enhance synaptic efficiency by positively modulating the function of . Synaptic dysfunction, with the consequent disruption of connectivity bet ween brain regions, underlies cognitive impairment seen in multiple CNS . For more information about AbbVie, please visit us atwww.abbvie.com. - Expands AbbVie's neuroscience portfolio, adding first-in-class modulators of the synaptic vesicle protein 2A, including lead molecule SDI-118 currently in Phase 1b studies. When typing in this field, a list of search results will appear and be automatically updated as you type. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Regulating synaptic transmission represents a promising approach to treating Alzheimers Disease and other disorders with cognitive impairment. Cleary Gottlieb Steen & Hamilton LLP acted as legal counsel to AbbVie. Syndesi's Series A financing was co-led by Novo Holdings together with Fountain Healthcare Partners, with participation from Johnson & Johnson Innovation JJDC, Inc., SRIW (Socit Rgionale d'Investissement de Wallonie), V-Bio Ventures and Vives Fund, along with UCB Ventures. Goodwin Procter LLP acted as lead legal counsel, along with Deloitte Legal, Belgium, and Lazard acted as the exclusive financial adviser to Syndesi. AbbVie has acquired Belgium-based company Syndesi Therapeutics in a deal worth up to $1bn, expanding its neuroscience portfolio.. Synaptic dysfunction is believed to underlie the cognitive impairment seen in multiple neuropsychiatric and neurodegenerative disorders. Personalize which data points you want to see and create visualizations instantly. This area is reserved for members of the news media. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Syndesi Therapeutics is building upon a rich legacy of research on SV2A conducted at UCB. Follow @abbvie on Twitter, Facebook, Instagram, YouTubeand LinkedIn. "There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases," saidTom Hudson, M.D., senior vice president, R&D, chief scientific officer, AbbVie. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Syndesi's unique molecules act pre-synaptically to enhance synaptic efficiency by . They are also entitled to get further contingent payments of up to $870m on meeting specific pre-set milestones. The North Chicago-based pharmaceutical giant (NYSE: ABBV . North Chicago, Illinois-based AbbVie announced Tuesday that it paid $130 million up front to acquire Syndesi Therapeutics. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. The company has also benefited from support from the Walloon Region. Synaptic dysfunction is believed to underlie the cognitive impairment seen in multiple neuropsychiatric and neurodegenerative disorders. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. No use of any AbbVie trademark, trade name, or trade dress in this site may be made without the prior written authorization of AbbVie Inc., except to identify the product or services of the company. Get the latest business insights from Dun & Bradstreet. from 8 AM - 9 PM ET. The "Yes" link below will take you out of the AbbVie family of websites. The UK Life Sciences team advised Syndesi Therapeutics and its shareholders on Syndesi's acquisition by AbbVie (NYSE: ABBV). Cleary Gottlieb Steen & Hamilton LLP acted as legal counsel to AbbVie. Solutions. AbbVie will pay Syndesi shareholders an upfront payment of $130m as part . Btiment Le Parc On Mar 2, 2022. Now, as part of AbbVie, the program is well positioned to move into later stages of clinical development.". AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those indicated in the forward-looking statements. Contact Email info@syndesitherapeutics.com. The lead molecule, SDI-118, was discovered by UCB before being out-licensed to Syndesi as of 2018. Our name Syndesi comes from the Greek for connection. Our Vision. Syndesi Therapeutics is building upon a rich legacy of research on SV2A conducted at UCB. Name of the organization that made the acquisition, Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. The total value of the deal could rise . Follow @abbvie on Twitter, Facebook, Instagram, YouTubeand LinkedIn. AbbVie has bolstered its neuropsychiatric and neurodegenerative portfolio with the acquisition of Belgium-based Syndesi Therapeutics in a deal valued at up to $1 billion. Syndesi's Series A financing was co-led by Novo Holdings together with Fountain Healthcare Partners, with participation from Johnson & Johnson Innovation JJDC, Inc., SRIW (Socit Rgionale d'Investissement de Wallonie), V-Bio Ventures and Vives Fund, along with UCB Ventures. 12401 Wilshire Blvd. We are creating a new and unique treatment approach using differentiated bone-forming cells. In-Line Products . Launching Soon Launching Soon Launching Soon Launching Soon . UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Syndesi Therapeutics is developing molecules which act in a unique way on the synaptic vesicle protein SV2A. Syndesi Therapeutics is funded by 9 investors. Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. Alzheimer's Therapeutics Research Leader Dr. Roy Twyman Joins NeuroVision Imaging Board. Syndesi Therapeutics General Information. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. PitchBooks non-financial metrics help you gauge a companys traction and growth using web presence and social reach. The mechanism is currently being evaluated . The deal will expand AbbVie 's neurological . Regulating synaptic transmission represents . Syndesi's unique molecules act pre-synaptically to enhance synaptic efficiency by positively modulating the function of synaptic vesicle protein 2A (SV2A), which plays a central role in regulating neurotransmission. With our robust radiopharmaceutical production and distribution network, mature contract manufacturing services, and now, high value radiopharmaceutical intellectual property, we are poised to deliver on the promise of . The information in the press releases on these pages was factually accurate on the date of publication. AbbVie will pay Syndesi's shareholders a $130 million upfront payment with the potential for Syndesi's shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2021 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its subsequent Quarterly Reports on Form 10-Q. Jonathan Savidge, Chief Executive Officer, Syndesi Therapeutics, said: "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of SDI-118 in a range of neurologic diseases. AbbVie has bolstered its neuropsychiatric and neurodegenerative portfolio with the acquisition of Belgium-based Syndesi Therapeutics in a deal valued at up to $1 billion. AbbVie Inc. said it's purchased a Belgian maker of neuroscience drugs in a deal that could be worth as much as $1 billion. For more information about AbbVie, please visit us atwww.abbvie.com. Subscription management. | Syndesi has an exclusive license to its . Twyman Served as Senior Vice President at Janssen Pharmaceutical Research & Development, Overseeing . | Such risks and uncertainties include, but are not limited to, failure to realize the expected benefits from AbbVie's acquisition of Allergan plc ("Allergan"), failure to promptly and effectively integrate Allergan's businesses, competition from other products, challenges to intellectual property, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry and the impact of public health outbreaks, epidemics or pandemics, such as COVID-19. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. According to the deal, shareholders of Syndesi will receive an upfront payment of $130m from AbbVie. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. The mechanism is currently being evaluated for . SV2A plays a central role in synaptic transmission (connections between neurons). Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The Internet site that you have requested may not be optimized to your screen size. Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. Published on March 6, 2022. 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